Tuesday, May 30, 2006

I have a job for inventors

How about designing some medical gyncological equipment that is made for people who DO NOT have a straight cervix.

So the biopsy is done. Did we have problems - of course. As my Doctor said at the end, the problem is that in the past we have been able to use cathedars which are flexible and can bend around the cervix (and remember in the past there has been lots of problems) but today we have to use straight tools. There was much trying and cursing and clamping down my cervix but eventually she was able to get a couple pieces of my lining.

She has put a rush on the results because I want to do the next FET next cycle but she now has concerns about whether we can do a natural cycle.

According to her my hormones are not playing together well. On day 18 my LH surged and told the brain to release the egg. However, at that point the egg was only 1.7, well short of maturity and too small to be fertilized. My estrogen level was just over 700 when she would like to see it at 1000 or more. My lining however, grew appropriately and was ready and waiting when LH surged. So today's biopsy should tell her if the hormones inside my uterus are ok or "out of phase" like the rest.

If the hormones from today's sample are ok, then we can proceed with a natural FET and pay more attention to when the lining is ready than the size of the egg.

However, if the hormones in the lining are in phase with the blood hormones, then we cannot do a natural FET becuase the conditions will never come together at the same time for implantation.

Plan B would be another medicated FET. During my last medicated FET, we used the long Ottawa protocal which involved a shot of provera on day 21 to bring on my period and shut down my hormones. Then I took increasing doses of Estrace throughout the month to mimic ovulation and build my lining. Only problem is that my body did not like the Provera. We had to hold off transfer for 5 days because my lining refused to get to .8. Then we had all kinds of problems with the progesterone level.

In a normal cycle, I have egg problems, but my lining and progesterone are fine. My doctor thinks that I am sensitive to the drugs. She blames my sensitivity for the 31 follicles that I developed and for the very high estrogen level (above 10,000) during IVF.

She thinks that the reason we had so much problem with the medicated FET was because I was so sensitive to the Provera that my body refused to allow the Estract to do it's job. It was over supressed. During the IVF we didn't use Provera for supression we used Suprefact.

If my biopsy comes back suggesting that the hormones are out of whack, she proposes we do a short medicated cycle. She would modify the protocal such that there would be no suppression. I would start very low dose estrace at the beginning of my cycle, hopefully enough to get the egg to healthy size and estrogen level up to 1000. Follow the cycle with dildo cam and wait for ovulation to happen naturally, then 5 days after ovulation, insert frosties.

This protocal appeals to my common sense. I have gained a tremendous amount of information from doing this "mock" cycle and wish that she had suggested it from the beginning. She told me today that because Rick and I have no medical issues, are relatively young and in relatively good shape, she assumed that low level treatment would work. I guess I understand that but perhaps she could have recomended the mock cycle before the IVF.

I am glad I insisted on the biopsy. My doctor said today that she is glad we did it too.

Only problem is, I am getting impatient. My doctor ordered the biopsy results stat, so she is hoping to get them by the end of the week. However, if I get my period before they get here, we may lose our chance to do the medicated protocol, as you have to start the estrace in the first couple cycle days.

I don't want to wait a whole month to start this treatment. I've been good - Let's get this show on the road!

3 comments:

Anonymous said...

It sometimes feels like an infertile's life is reduced to waiting. It's so frustrating. I hope things move along for you ASAP.

MoMo said...

Krista--sounds like you have everything covered-I totally understand that this is all about the waiting game. Hang in there!

Maya said...

Aye, aye, aye - sounds like quite a lot of procedures. I am glad that you are so well informed and take such good care of yourself. I'll be pulling for things to happen a lot sooner rather than later.